Cacna1htm2.1(cre)Glwn
Targeted Allele Detail
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Symbol: |
Cacna1htm2.1(cre)Glwn |
Name: |
calcium channel, voltage-dependent, T type, alpha 1H subunit; targeted mutation 2.1, Gary R Lewin |
MGI ID: |
MGI:6759808 |
Synonyms: |
Cav3.2Cre |
Gene: |
Cacna1h Location: Chr17:25593259-25652759 bp, - strand Genetic Position: Chr17, 12.53 cM
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Alliance: |
Cacna1htm2.1(cre)Glwn page
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Germline Transmission: |
Earliest citation of germline transmission:
J:309445
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout, Recombinase) |
Mutation: |
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Insertion
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Cacna1htm2.1(cre)Glwn expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: Targeting vectors to insert cre expression cassette after the start codon of the Cacna1h (Cav3.2) gene located at the second exon was used to generate the allele by homologous recombination in ES cells. The insertion of the cre cassettes produces a null mutation of the Cacna1h gene. The neo cassette was removed by flpe recombinase.
(J:309445)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Cacna1h
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cacna1h Mutation: |
98 strains or lines available
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Original: |
J:309445 Bernal Sierra YA, et al., Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System. Front Mol Neurosci. 2017;10:70 |
All: |
1 reference(s) |
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