Tg(Actb-SLC15A1)#Merl
Transgene Detail

Summary

• Symbol: Tg(Actb-SLC15A1)#Merl
• Name: transgene insertion, Didier Merlin
• MGI ID: MGI:6758772
• Synonyms: beta-actin-hPepT1
• Transgene: Tg(Actb-SLC15A1)#Merl Location: unknown
• Alliance: Tg(Actb-SLC15A1)#Merl page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Actb-SLC15A1)#Merl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SLC15A1 (6564)

  Slc15a1

  (MGI:1861376)

  mouse promoter, human HA-tagged cDNA

• Mutation details: This construct contains the mouse beta actin promoter and intron 1, sequence for 3x HA tags in-frame with human solute carrier family 15 (oligopeptide transporter) member 1 cDNA and SV40 poly(A) signal sequences. (J:309572)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:309572 Dalmasso G, et al., The PepT1-NOD2 signaling pathway aggravates induced colitis in mice. Gastroenterology. 2011 Oct;141(4):1334-45
• All: 1 reference(s)