Tg(MMTV-MED1)2Xiz
Transgene Detail

Summary

• Symbol: Tg(MMTV-MED1)2Xiz
• Name: transgene insertion 2, Xiaoting Zhang
• MGI ID: MGI:6758541
• Synonyms: MMTV-MED1
• Transgene: Tg(MMTV-MED1)2Xiz Location: unknown
• Alliance: Tg(MMTV-MED1)2Xiz page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTV-MED1)2Xiz expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MED1 (5469)

  Med1	(MGI:1100846)

  human cDNA

• Mutation details: This construct comprises the following elements: the mouse mammary tumor virus LTR, beta globin exon 2, intron 2 and exon 3, the human mediator complex subunit 1 cDNA and beta globin exon 3 and poly(A) signal sequences. (J:306410)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:306410 Yang Y, et al., Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell Rep. 2021 Mar 9;34(10):108822
• All: 1 reference(s)