Snap23^tm1.2Aha
Targeted Allele Detail

Summary

• Symbol: Snap23^tm1.2Aha
• Name: synaptosomal-associated protein 23; targeted mutation 1.2, Akihiro Harada
• MGI ID: MGI:6758209
• Gene: Snap23 Location: Chr2:120398152-120431736 bp, + strand Genetic Position: Chr2, 60.37 cM, cytoband E5
• Alliance: Snap23^tm1.2Aha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306995
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct introduced a loxP site downstream of exon 2 and an FRT-flanked neomycin resistance cassette with a 3' loxP site downstream of exon 5. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination deleted exons 3 through 5 floxed. (J:306995)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snap23 Mutation: 32 strains or lines available

References

• Original: J:306995 Kunii M, et al., Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells. J Cell Biol. 2016 Oct 10;215(1):121-138
• All: 1 reference(s)