Trpc5tm1.1(cre)Dbru
Targeted Allele Detail
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Symbol: |
Trpc5tm1.1(cre)Dbru |
Name: |
transient receptor potential cation channel, subfamily C, member 5; targeted mutation 1.1, Dieter Bruns |
MGI ID: |
MGI:6758141 |
Synonyms: |
TRPC5-IC, TRPC5-IRES-Cre |
Gene: |
Trpc5 Location: ChrX:143164667-143471176 bp, - strand Genetic Position: ChrX, 65.49 cM, cytoband F2
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Alliance: |
Trpc5tm1.1(cre)Dbru page
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Trpc5tm1.1(cre)Dbru expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Trpc5 (MGI:109524) |
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Mutation details: The targeting construct inserted an IRES-Cre-pgk promoterdriven Flp recombination target (FRT)neomycin (neo)FRT cassette into final exon 11 of the Trpc5 gene by homologous recombination in ES cells. The FRT flanked neo selection cassette was removed by FLP-deleter mice.
(J:287788)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Trpc5
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Trpc5 Mutation: |
19 strains or lines available
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Original: |
J:287788 Schwarz Y, et al., TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses. PLoS Biol. 2019 Sep;17(9):e3000445 |
All: |
2 reference(s) |
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