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Tg(tetO-ERBB2*)#Mul
Transgene Detail
Summary
Symbol: Tg(tetO-ERBB2*)#Mul
Name: transgene insertion, William Muller
MGI ID: MGI:6758103
Transgene: Tg(tetO-ERBB2*)#Mul  Location: unknown  
Alliance: Tg(tetO-ERBB2*)#Mul page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsA DNA fragment containing the Tet-responsive promoter driving human ERBB2 containing an in-frame deletion of exon 16 (ErbB2Ex16) cDNA was used to generate the transgene. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:309306)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:309306 Turpin J, et al., The ErbB2DeltaEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment. Oncogene. 2016 Nov 24;35(47):6053-6064
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory