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Anxa10tm1.1(cre/ERT2)Dstan
Targeted Allele Detail
Summary
Symbol: Anxa10tm1.1(cre/ERT2)Dstan
Name: annexin A10; targeted mutation 1.1, Daniel E Stange
MGI ID: MGI:6758084
Synonyms: Anxa10-CreERT2
Gene: Anxa10  Location: Chr8:62510076-62576184 bp, - strand  Genetic Position: Chr8, 31.55 cM
Alliance: Anxa10tm1.1(cre/ERT2)Dstan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:309130
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Anxa10tm1.1(cre/ERT2)Dstan expression driven by 1 gene
 
Mutation detailsAn IRESCreERT2 and a PGK-Neo cassette flanked by FRT site were inserted after the stop codon of the last exon 12 of the Anxa10 gene by homologous recombination in C57BL/6 ES cells. The PGK-Neo cassette was removed by crossing to FLP expressing mice. (J:309130)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Anxa10 (mouse)
Summary of all recombinase alleles driven by Anxa10.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Anxa10 Mutation:  28 strains or lines available
References
Original:  J:309130 Seidlitz T, et al., Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations. Gastroenterology. 2019 Dec;157(6):1599-1614.e2
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory