Nphs2^{tm1(cre/ERT2)Smoc}
Targeted Allele Detail

Summary

• Symbol: Nphs2^{tm1(cre/ERT2)Smoc}
• Name: nephrosis 2, podocin; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6758036
• Synonyms: Nphs2-CreERT2, Nphs2^{tm1(IRES-CreERT2)Smoc}
• Gene: Nphs2 Location: Chr1:156138297-156155605 bp, + strand Genetic Position: Chr1, 67.71 cM, cytoband G3
• Alliance: Nphs2^{tm1(cre/ERT2)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Nphs2^{tm1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nphs2 (MGI:2157018)

• Mutation details: An IRES-CreERT2 co-expression cassette is inserted into the 3'UTR region of the Nphs2 gene via homologous recombination. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nphs2 (mouse) Summary of all recombinase alleles driven by Nphs2. Alliance mouse Nphs2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nphs2 Mutation: 30 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)