Tg(tetO-d2EGFP,-Shh)#Ohts
Transgene Detail
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Symbol: |
Tg(tetO-d2EGFP,-Shh)#Ohts |
Name: |
transgene insertion, Toshiyuki Ohtsuka |
MGI ID: |
MGI:6756396 |
Synonyms: |
TRE-mShh/d2EGFP |
Transgene: |
Tg(tetO-d2EGFP,-Shh)#Ohts Location: unknown
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Alliance: |
Tg(tetO-d2EGFP,-Shh)#Ohts page
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Strain of Origin: |
Not Applicable
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Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence, Reporter) |
Inducer: |
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doxycycline/tetracycline |
Mutation: |
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Insertion
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Tg(tetO-d2EGFP,-Shh)#Ohts expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Shh (MGI:98297) |
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Mutation details: In this construct, the tetO tetracycline responsive element (TRE) was placed between the modified d2EGFP reporter gene and the mouse sonic hedgehog cDNA. The two genes are arranged in opposite transcriptional orientation (head-to-head) and the SV40 poly(A) signal sequence was placed 3' of each.
(J:306455)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:306455 Shqirat M, et al., Sonic hedgehog expands neural stem cells in the neocortical region leading to an expanded and wrinkled neocortical surface. Genes Cells. 2021 Jun;26(6):399-410 |
All: |
2 reference(s) |
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