Pou2f3tm1.1(cre/ERT2)Imt
Targeted Allele Detail
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Symbol: |
Pou2f3tm1.1(cre/ERT2)Imt |
Name: |
POU domain, class 2, transcription factor 3; targeted mutation 1.1, Ichiro Matsumoto |
MGI ID: |
MGI:6755141 |
Synonyms: |
Pou2f3-CreERT2-ires-EGFP |
Gene: |
Pou2f3 Location: Chr9:43035222-43117052 bp, - strand Genetic Position: Chr9, 24.21 cM
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Alliance: |
Pou2f3tm1.1(cre/ERT2)Imt page
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Germline Transmission: |
Earliest citation of germline transmission:
J:288632
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6J
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Pou2f3tm1.1(cre/ERT2)Imt expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pou2f3 (MGI:102565) |
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Mutation details: A CreERT2-ires-EGFP followed by an FRT-flanked PGK-Neo cassette was inserted by homologous recombination in place of the initial ATG codon of the Pou2f3 gene of C57BL/6J-derived ES cells. Chimeric mice were mated with an FLP strain to remove the PGK-Neo cassette.
(J:288632)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pou2f3
(mouse)
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Original: |
J:288632 McGinty JW, et al., Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. Immunity. 2020 Mar 17;52(3):528-541.e7 |
All: |
1 reference(s) |
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