Bbs5^{tm1d(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Bbs5^{tm1d(EUCOMM)Wtsi}
• Name: Bardet-Biedl syndrome 5; targeted mutation 1d, Wellcome Trust Sanger Institute
• MGI ID: MGI:6741143
• Synonyms: Bbs5^delta
• Gene: Bbs5 Location: Chr2:69477515-69497915 bp, + strand Genetic Position: Chr2, 40.91 cM, cytoband C3
• Alliance: Bbs5^{tm1d(EUCOMM)Wtsi} page
• IMPC: Bbs5 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307098
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination of Bbs5^{tm1c(EUCOMM)Wtsi} removed the loxP-flanked exons 4 and 5. (J:307098)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bbs5 Mutation: 17 strains or lines available

References

• Original: J:307098 Bentley-Ford MR, et al., A mouse model of BBS identifies developmental and homeostatic effects of BBS5 mutation and identifies novel pituitary abnormalities. Hum Mol Genet. 2021 Apr 26;30(3-4):234-246
• All: 1 reference(s)