Usp26^em2Liwe
Endonuclease-mediated Allele Detail

Summary

• Symbol: Usp26^em2Liwe
• Name: ubiquitin specific peptidase 26; endonuclease-mediated mutation 2, Wei Li
• MGI ID: MGI:6740503
• Gene: Usp26 Location: ChrX:50842836-50890110 bp, - strand Genetic Position: ChrX, 28.31 cM
• Alliance: Usp26^em2Liwe page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 16bp deletion in exon 9. (J:308679)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp26 Mutation: 6 strains or lines available

References

• Original: J:308679 Liu C, et al., Paternal USP26 mutations raise Klinefelter syndrome risk in the offspring of mice and humans. EMBO J. 2021 Jul 1;40(13):e106864
• All: 1 reference(s)