Aviltm1.1(flpo)Ddg
Targeted Allele Detail
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Symbol: |
Aviltm1.1(flpo)Ddg |
Name: |
advillin; targeted mutation 1.1, David D Ginty |
MGI ID: |
MGI:6740440 |
Synonyms: |
AdvillinFlpO |
Gene: |
Avil Location: Chr10:126836578-126856863 bp, + strand Genetic Position: Chr10, 74.48 cM, cytoband D3
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Alliance: |
Aviltm1.1(flpo)Ddg page
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Germline Transmission: |
Earliest citation of germline transmission:
J:290819
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Aviltm1.1(flpo)Ddg expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A Flpo recombinase cassettes were introduced via homologous recombination into the Avil genes, replacing the first coding ATG. The recombinase is driven by Avil in somatosensory and other peripheral nervous system neurons. The neomycin selection cassette was removed by recombination.
(J:290819, J:297417)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Avil
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Avil Mutation: |
46 strains or lines available
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Original: |
J:290819 Neubarth NL, et al., Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception. Science. 2020 Jun 19;368(6497) |
All: |
7 reference(s) |
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