Ctsd^tm1.1Ohmu
Targeted Allele Detail

Summary

• Symbol: Ctsd^tm1.1Ohmu
• Name: cathepsin D; targeted mutation 1.1, Masaki Ohmuraya
• MGI ID: MGI:6730082
• Gene: Ctsd Location: Chr7:141929647-141941564 bp, - strand Genetic Position: Chr7, 87.93 cM
• Alliance: Ctsd^tm1.1Ohmu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:290675
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct floxed exon 2. Cre-mediated recombination removed exon 2. (J:290675)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctsd Mutation: 21 strains or lines available

References

• Original: J:290675 Suzuki C, et al., Lack of Cathepsin D in the Renal Proximal Tubular Cells Resulted in Increased Sensitivity against Renal Ischemia/Reperfusion Injury. Int J Mol Sci. 2019 Apr 5;20(7):1711
• All: 1 reference(s)