Ctsd^tm1Ohmu
Targeted Allele Detail

Summary

• Symbol: Ctsd^tm1Ohmu
• Name: cathepsin D; targeted mutation 1, Masaki Ohmuraya
• MGI ID: MGI:6730072
• Synonyms: CD^f
• Gene: Ctsd Location: Chr7:141929647-141941564 bp, - strand Genetic Position: Chr7, 87.93 cM
• Alliance: Ctsd^tm1Ohmu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233172
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 2. (J:233172)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctsd Mutation: 21 strains or lines available

References

• Original: J:233172 Mehanna S, et al., Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity. Biochem Biophys Res Commun. 2016 Jan 15;469(3):405-11
• All: 3 reference(s)