Git1^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Git1^em1Gpt
• Name: GIT ArfGAP 1; endonuclease-mediated mutation 1, GemPharmatech
• MGI ID: MGI:6729908
• Synonyms: Git1^em1Cflox, GIT1^fl
• Gene: Git1 Location: Chr11:77384388-77398612 bp, + strand Genetic Position: Chr11, 46.61 cM
• Alliance: Git1^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 2 through 7. (J:297330)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Git1 Mutation: 43 strains or lines available

References

• Original: J:297330 Zhao SJ, et al., Macrophage GIT1 Contributes to Bone Regeneration by Regulating Inflammatory Responses in an ERK/NRF2-Dependent Way. J Bone Miner Res. 2020 Oct;35(10):2015-2031
• All: 1 reference(s)