Akt3^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Akt3^em1Smoc
• Name: Akt serine/threonine kinase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6729706
• Gene: Akt3 Location: Chr1:176847639-177085769 bp, - strand Genetic Position: Chr1, 82.66 cM, cytoband H4-H6
• Alliance: Akt3^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 3 through 5. (J:304160)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Akt3 Mutation: 40 strains or lines available

References

• Original: J:304160 Gu S, et al., AKT3 deficiency in M2 macrophages impairs cutaneous wound healing by disrupting tissue remodeling. Aging (Albany NY). 2020 Apr 14;12(8):6928-6946
• All: 1 reference(s)