Tg(Ncr1-cre/ERT2)#Lll
Transgene Detail

Summary

• Symbol: Tg(Ncr1-cre/ERT2)#Lll
• Name: transgene insertion, Lewis L Lanier
• MGI ID: MGI:6729263
• Synonyms: NKp46-CreERT2 Tg
• Transgene: Tg(Ncr1-cre/ERT2)#Lll Location: unknown
• Alliance: Tg(Ncr1-cre/ERT2)#Lll page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Ncr1-cre/ERT2)#Lll expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ncr1 (MGI:1336212)

• Mutation details: The transgene consisting of a bacterial artificial chromosome (BAC) clone RP23-267N11 that encodes mouse chromosome 7 was modified to insert an internal ribosome entry site (IRES)-CreERT2 cassette into the 3 untranslated region of exon 7 of the mouse Ncr1 gene. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:237515)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ncr1 (mouse) Summary of all recombinase alleles driven by Ncr1. Comparative matrix view of recombinase activities Alliance mouse Ncr1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:237515 Nabekura T, et al., Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection. J Exp Med. 2016 Nov 14;213(12):2745-2758
• All: 2 reference(s)