Tlr4^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tlr4^em1Gpt
• Name: toll-like receptor 4; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6729209
• Synonyms: Tlr4^em1Cd
• Gene: Tlr4 Location: Chr4:66745788-66765338 bp, + strand Genetic Position: Chr4, 34.66 cM
• Alliance: Tlr4^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting deleted a portion of the coding region to produce a null allele. (J:304134)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tlr4 Mutation: 95 strains or lines available

References

• Original: J:304134 Han C, et al., Smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy. Cell Rep. 2021 Feb 9;34(6):108706
• All: 3 reference(s)