Kynu^em1Llp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kynu^em1Llp
• Name: kynureninase; endonuclease-mediated mutation 1, Luanne L Peters
• MGI ID: MGI:6728065
• Gene: Kynu Location: Chr2:43445341-43572734 bp, + strand Genetic Position: Chr2, 25.64 cM, cytoband C1
• Alliance: Kynu^em1Llp page

Mutation origin

• Strain of Origin: C57BL/6NJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated by microinjecting cas9 and guide sequences GATGCAGTGCGGCGCATCG and GTTGCTCTCCGCTTGGATG resulting in a 149 bp deletion that includes the first 127 bp of Exon 2 and some of the preceding intron. (J:308097)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kynu Mutation: 34 strains or lines available

References

• Original: J:308097 Robledo RF, et al., Personal Communication concerning Kynu^em1Llp. Personal Communication. 2021
• All: 1 reference(s)