Tg(Runx1/Hspa1a-EGFP)#Mosa
Transgene Detail

Summary

• Symbol: Tg(Runx1/Hspa1a-EGFP)#Mosa
• Name: transgene insertion, Motomi Osato
• MGI ID: MGI:6726477
• Synonyms: eR1-EGFP, eR1-mHSP68-EGFP, Runx1 +24 mCNE
• Transgene: Tg(Runx1/Hspa1a-EGFP)#Mosa Location: unknown
• Alliance: Tg(Runx1/Hspa1a-EGFP)#Mosa page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgenic construct contains mouse Runx1 enhancer element sequence (eR1) also called Runx1 +24 mouse conserved noncoding element (mCNE) and the mouse Hspa1a (heat-shock protein 68) basal promoter sequence driving the expression of EGFP. Three distinct founder lines numbered 523, 540, and 542 were established. Although variation in the intensity of GFP fluorescence was observed, all three lines showed similar reporter gene expression patterns at sites of hematopoietic stem cell emergence in embryos. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:307859)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:307859 Ng CE, et al., A Runx1 intronic enhancer marks hemogenic endothelial cells and hematopoietic stem cells. Stem Cells. 2010 Oct;28(10):1869-81
• All: 6 reference(s)