Cux2^tm1.2Kess
Targeted Allele Detail

Summary

• Symbol: Cux2^tm1.2Kess
• Name: cut-like homeobox 2; targeted mutation 1.2, Nicoletta Kessaris
• MGI ID: MGI:6726113
• Synonyms: Cux2^delta
• Gene: Cux2 Location: Chr5:121996025-122188522 bp, - strand Genetic Position: Chr5, 62.02 cM
• Alliance: Cux2^tm1.2Kess page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306613
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed exons 22 through 23. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 22 through 23. (J:306613)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cux2 Mutation: 44 strains or lines available

References

• Original: J:306613 Magno L, et al., Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior. Cell Rep. 2021 Jun 15;35(11):109249
• All: 1 reference(s)