Oxttm1.1(flpo)Cya
Targeted Allele Detail
|
Symbol: |
Oxttm1.1(flpo)Cya |
Name: |
oxytocin; targeted mutation 1.1, Cyagen Biosciences |
MGI ID: |
MGI:6726072 |
Synonyms: |
OT-2A-Flp KI, Oxttm1.1(flpo)Cgen |
Gene: |
Oxt Location: Chr2:130418093-130418974 bp, + strand Genetic Position: Chr2, 63.24 cM
|
Alliance: |
Oxttm1.1(flpo)Cya page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:301094
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Recombinase) |
Mutation: |
|
Insertion
|
|
|
Oxttm1.1(flpo)Cya expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Oxt (MGI:97453) |
|
|
|
|
Mutation details: The stop codon in exon 3 of the endogenous oxytocin gene (Oxt) was replaced with a 2A-flpo construct. A neo selection cassette was removed by cre recombination.
(J:301094)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
Oxt
(mouse)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Oxt Mutation: |
20 strains or lines available
|
|
Original: |
J:301094 Nardou R, et al., Oxytocin-dependent reopening of a social reward learning critical period with MDMA. Nature. 2019 May;569(7754):116-120 |
All: |
2 reference(s) |
|