Cnot6^em1Hyfn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cnot6^em1Hyfn
• Name: CCR4-NOT transcription complex, subunit 6; endonuclease-mediated mutation 1, Heng-Yu Fan
• MGI ID: MGI:6725739
• Gene: Cnot6 Location: Chr11:49562330-49603550 bp, - strand Genetic Position: Chr11, 29.76 cM
• Alliance: Cnot6^em1Hyfn page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3 deleted 640 bp including the exon. (J:307645)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnot6 Mutation: 42 strains or lines available

References

• Original: J:307645 Dai XX, et al., The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis. Adv Sci (Weinh). 2021 May;8(10):2003636
• All: 2 reference(s)