Del(10Dux-Gm4981)1Yzhg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(10Dux-Gm4981)1Yzhg
• Name: deletion, chr 10, Yi Zhang 1; deletion, Chr 10, Yi Zhang 1
• MGI ID: MGI:6724566
• Gene: Del(10Dux-Gm4981)1Yzhg Location: unknown Genetic Position: Chr10, Syntenic

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Del(10Dux-Gm4981)1Yzhg involves 2 genes/genome features (Dux, Duxf4) View all
• CRISPR-targeting deleted a segment including the Dux-containing macrosatellite repeats and Gm4981. (J:281829)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(10Dux-Gm4981)1Yzhg Mutation: 0 strains or lines available

References

• Original: J:281829 Chen Z, et al., Loss of DUX causes minor defects in zygotic genome activation and is compatible with mouse development. Nat Genet. 2019 Jun;51(6):947-951
• All: 1 reference(s)