Qtrt1^em1Tuo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Qtrt1^em1Tuo
• Name: queuine tRNA-ribosyltransferase catalytic subunit 1; endonuclease-mediated mutation 1, Francesca Tuorto
• MGI ID: MGI:6724475
• Gene: Qtrt1 Location: Chr9:21323133-21331570 bp, + strand Genetic Position: Chr9, 7.79 cM, cytoband A4
• Alliance: Qtrt1^em1Tuo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:339124
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting inserted a T in the third coding exon. (J:339124)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Qtrt1 Mutation: 24 strains or lines available

References

• Original: J:339124 Cirzi C, et al., Queuosine-tRNA promotes sex-dependent learning and memory formation by maintaining codon-biased translation elongation speed. EMBO J. 2023;:e112507
• All: 1 reference(s)