Gata4tm2(cre/ERT2)Ykaw
Targeted Allele Detail
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Symbol: |
Gata4tm2(cre/ERT2)Ykaw |
Name: |
GATA binding protein 4; targeted mutation 2, Yoshiya Kawaguchi |
MGI ID: |
MGI:6724013 |
Synonyms: |
Gata4CreERT2 |
Gene: |
Gata4 Location: Chr14:63436371-63509141 bp, - strand Genetic Position: Chr14, 33.24 cM
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Alliance: |
Gata4tm2(cre/ERT2)Ykaw page
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase) |
Inducer: |
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tamoxifen |
Mutations: |
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Insertion, Intragenic deletion
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Gata4tm2(cre/ERT2)Ykaw expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Gata4 (MGI:95664) |
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Mutation details: A CreERT2-pA-PGK-Bsd-pA replaced most of exon 1 after the first ATG of the Gata4 gene via homologous recombination in ES cells.
(J:301269)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Gata4
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gata4 Mutation: |
36 strains or lines available
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Original: |
J:301269 Sankoda N, et al., Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560 |
All: |
1 reference(s) |
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