Tg(Tcrb31.2.10)#Gifr
Transgene Detail

Summary

• Symbol: Tg(Tcrb31.2.10)#Gifr
• Name: transgene insertion, Giulia Freer
• MGI ID: MGI:6723899
• Synonyms: ADA
• Transgene: Tg(Tcrb31.2.10)#Gifr Location: unknown
• Alliance: Tg(Tcrb31.2.10)#Gifr page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tcrb31.2.10)#Gifr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcrb (MGI:98578)

• Mutation details: The transgene comprises the MHC class II (I-A^b)-restricted TCR specific for a peptide derived from the glycoprotein (G) of vesicular stomatitis virus serotype Indiana (VSV-IND), derived from the Vb2⁺ T cell hybridoma 31.2.10 Tcrb gene (leader, Vb2, Db1.1, Jb2.1, Cb2) . The TCR sequence was preceded by the H2-K^b promoter and followed by beta globin intron 2, poly(A) signal sequences and an Igh enhancer. (J:307526)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:307526 Freer G, et al., Role of T helper cell precursor frequency on vesicular stomatitis virus neutralizing antibody responses in a T cell receptor beta chain transgenic mouse. Eur J Immunol. 1995 May;25(5):1410-6
• All: 1 reference(s)