Tg(H2-K^b-FUT1)#Ajfda
Transgene Detail

Summary

• Symbol: Tg(H2-K^b-FUT1)#Ajfda
• Name: transgene insertion, Anthony J F d'Apice
• MGI ID: MGI:6723828
• Transgene: Tg(H2-K^b-FUT1)#Ajfda Location: unknown
• Alliance: Tg(H2-K^b-FUT1)#Ajfda page

Transgene origin

• Strain of Origin: (CBA x C57BL/6)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-K^b-FUT1)#Ajfda expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FUT1 (2523)

  Fut1	(MGI:109375)

  mouse promoter, human cDNA

• Mutation details: This transgene contains the following elements: the mouse histocompatibility 2 K region (H2-K^b) promoter, a hybrid intron (AML virus 3' end of 5' UTR exon and 5' end of intron 1 plus Igh-V splice acceptor), the human fucosyltransferase 1 (H blood group) cDNA and SV40 late poly(A) signal sequences. (J:307477)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:307477 Chen C-G, et al., Reduction in Gal-alpha1,3-Gal epitope expression in transgenic mice expressing human H-transferase. Xenotransplantation. 1996;3:69-75
• All: 3 reference(s)