Emx2^em1Btar
Endonuclease-mediated Allele Detail

Summary

• Symbol: Emx2^em1Btar
• Name: empty spiracles homeobox 2; endonuclease-mediated mutation 1, Basile Tarchini
• MGI ID: MGI:6723827
• Gene: Emx2 Location: Chr19:59447122-59453789 bp, + strand Genetic Position: Chr19, 56.28 cM
• Alliance: Emx2^em1Btar page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a approximately 500 bp deletion in exon 1 encompassing the entire coding region of exon 1. (J:306060)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Emx2 Mutation: 23 strains or lines available

References

• Original: J:306060 Kindt KS, et al., EMX2-GPR156-Galphai reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021 May 17;12(1):2861
• All: 1 reference(s)