Muc2^em1Ktak
Endonuclease-mediated Allele Detail

Summary

• Symbol: Muc2^em1Ktak
• Name: mucin 2; endonuclease-mediated mutation 1, Kiyoshi Takeda
• MGI ID: MGI:6723782
• Gene: Muc2 Location: Chr7:141276583-141308428 bp, + strand Genetic Position: Chr7, 87.1 cM, cytoband F5
• Alliance: Muc2^em1Ktak page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 produced a null allele. (J:307058)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Muc2 Mutation: 86 strains or lines available

References

• Original: J:307058 Hsu CC, et al., Alleviation of colonic inflammation by Lypd8 in a mouse model of inflammatory bowel diseases (IBD). Int Immunol. 2021 Apr 5;33(7):359-372
• All: 2 reference(s)