Kdm5d^em1Okkm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kdm5d^em1Okkm
• Name: lysine demethylase 5D; endonuclease-mediated mutation 1, Tohru Kimura
• MGI ID: MGI:6723758
• Synonyms: Kdm5d^delta2
• Gene: Kdm5d Location: ChrY:897566-946316 bp, + strand Genetic Position: ChrY, cytoband p
• Alliance: Kdm5d^em1Okkm page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 deleted 2 bp producing premature termination of translation.. (J:307066)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm5d Mutation: 74 strains or lines available

References

• Original: J:307066 Kosugi M, et al., Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice. Biochem Biophys Res Commun. 2020 Feb 17
• All: 1 reference(s)