Zfp90^em1Jyf
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zfp90^em1Jyf
• Name: zinc finger protein 90; endonuclease-mediated mutation 1, Jing-Yuan Fang
• MGI ID: MGI:6721078
• Synonyms: Zfp90^fl
• Gene: Zfp90 Location: Chr8:107141959-107153230 bp, + strand Genetic Position: Chr8, 53.14 cM, cytoband D3
• Alliance: Zfp90^em1Jyf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303639
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting flanked exon 4 with loxP sites. (J:303639)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp90 Mutation: 29 strains or lines available

Notes

Lentiviral gene trap injected into zygotes.

References

• Original: J:303639 Yu CY, et al., A 16q22.1 variant confers susceptibility to colorectal cancer as a distal regulator of ZFP90. Oncogene. 2020 Feb;39(6):1347-1360
• All: 1 reference(s)