Vim^{em1(cre/ERT2)Bzsh}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vim^{em1(cre/ERT2)Bzsh}
• Name: vimentin; endonuclease-mediated mutation 1, Bin Zhou
• MGI ID: MGI:6720921
• Synonyms: Vim-CreER
• Gene: Vim Location: Chr2:13579122-13587637 bp, + strand Genetic Position: Chr2, 10.04 cM, cytoband A2
• Alliance: Vim^{em1(cre/ERT2)Bzsh} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Vim^{em1(cre/ERT2)Bzsh} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Vim (MGI:98932)

• Mutation details: A CreERT2 was inserted at the start codon (ATG site) via CRISPR/Cas9-mediated homologous recombination in ES cells. (J:278026)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Vim (mouse) Summary of all recombinase alleles driven by Vim. Comparative matrix view of recombinase activities Alliance mouse Vim gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vim Mutation: 37 strains or lines available

References

• Original: J:278026 Li Y, et al., Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases. Circulation. 2018 Aug 21;138(8):793-805
• All: 2 reference(s)