Tg(Cfap53/Venus)66Hmd
Transgene Detail

Summary

• Symbol: Tg(Cfap53/Venus)66Hmd
• Name: transgene insertion 66, Hiroshi Hamada
• MGI ID: MGI:6720862
• Synonyms: Cfap53^Venus
• Transgene: Tg(Cfap53/Venus)66Hmd Location: unknown
• Alliance: Tg(Cfap53/Venus)66Hmd page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: Using mouse BAC RP23-99F21, which contains the Cfap53 gene, sequence for (Gly₄Ser)₃ linker peptide, the Venus fluorescent protein gene sequence, poly(A) signal sequence and a loxP site were inserted immediately upstream of the Cfap53 stop codon in exon 8. Founder strain 66 carries one copy of this Cfap53-Venus fusion transgene. (J:301033)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:301033 Ide T, et al., CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components. PLoS Genet. 2020 Dec;16(12):e1009232
• All: 1 reference(s)