Paxx^em1Vokh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Paxx^em1Vokh
• Name: non-homologous end joining factor; endonuclease-mediated mutation 1, Valentyn Oksenych
• MGI ID: MGI:6720275
• Gene: Paxx Location: Chr2:25345153-25351106 bp, - strand Genetic Position: Chr2, 17.27 cM
• Alliance: Paxx^em1Vokh page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of the promoter and exon 2 deleted part of the promoter through exon 2 without affecting the overlapping gene. (J:278790)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Paxx Mutation: 9 strains or lines available

References

• Original: J:278790 Gago-Fuentes R, et al., Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF. FEBS Open Bio. 2018 Mar;8(3):426-434
• All: 2 reference(s)