Npr1^em1.1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Npr1^em1.1Smoc
• Name: natriuretic peptide receptor 1; endonuclease-mediated mutation 1.1, Shanghai Model Organisms Center
• MGI ID: MGI:6719491
• Gene: Npr1 Location: Chr3:90357898-90373173 bp, - strand Genetic Position: Chr3, 39.23 cM
• Alliance: Npr1^em1.1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR-targeting floxed exon 2. Cre-mediated recombination removed the selection cassette. (J:307074)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npr1 Mutation: 58 strains or lines available

References

• Original: J:307074 Chen B, et al., Cardiacspecific deletion of natriuretic peptide receptor A induces differential myocardial expression of circular RNA and mRNA molecules involved in metabolism in mice. Mol Med Rep. 2021 Jan;23(1)
• All: 1 reference(s)