Adk^tm1Xen
Targeted Allele Detail

Summary

• Symbol: Adk^tm1Xen
• Name: adenosine kinase; targeted mutation 1, Taconic Biosciences
• MGI ID: MGI:6719386
• Gene: Adk Location: Chr14:21102642-21498637 bp, + strand Genetic Position: Chr14, 11.58 cM, cytoband A2-B
• Alliance: Adk^tm1Xen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306562
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 7 was floxed via homologous recombination. (J:306562)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adk Mutation: 49 strains or lines available

References

• Original: J:306562 Wang Y, et al., Adenosine kinase is critical for neointima formation after vascular injury by inducing aberrant DNA hypermethylation. Cardiovasc Res. 2021 Jan 21;117(2):561-575
• All: 2 reference(s)