Spon2^em1Gul
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spon2^em1Gul
• Name: spondin 2, extracellular matrix protein; endonuclease-mediated mutation 1, Bayasi Guleng
• MGI ID: MGI:6719352
• Gene: Spon2 Location: Chr5:33370862-33375596 bp, - strand Genetic Position: Chr5, 17.5 cM
• Alliance: Spon2^em1Gul page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Crispr/cas mediated recombination resulted in the deletion of a CG and insertion of a T resulting in a frameshift mutation and premature stop codon. (J:306843)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spon2 Mutation: 23 strains or lines available

References

• Original: J:306843 Cheng XS, et al., Mindin serves as a tumour suppressor gene during colon cancer progression through MAPK/ERK signalling pathway in mice. J Cell Mol Med. 2020 Aug;24(15):8391-8404
• All: 1 reference(s)