Prap1^em2Yen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prap1^em2Yen
• Name: proline-rich acidic protein 1; endonuclease-mediated mutation 2, Hsin-Fang Yang-Yen
• MGI ID: MGI:6719336
• Synonyms: PRAP1^E85V
• Gene: Prap1 Location: Chr7:139673308-139677113 bp, + strand Genetic Position: Chr7, 85.1 cM, cytoband F5
• Alliance: Prap1^em2Yen page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR/Cas9 technology introduced a glutamate to valine substitution at residue 85 (E85V). This line was generated from founder 19. (J:306883)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prap1 Mutation: 14 strains or lines available

References

• Original: J:306883 Peng H, et al., PRAP1 is a novel lipid binding protein that promotes lipid absorption by facilitating MTTP-mediated lipid transport. J Biol Chem. 2020 Nov 9
• All: 1 reference(s)