Ets2^em3Aitn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ets2^em3Aitn
• Name: Ets proto-oncogene 2, transcription factor; endonuclease-mediated mutation 3, Ayako Isotani
• MGI ID: MGI:6719270
• Synonyms: Ets2^null
• Gene: Ets2 Location: Chr16:95503274-95522093 bp, + strand Genetic Position: Chr16, 56.64 cM, cytoband C3-qter
• Alliance: Ets2^em3Aitn page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted a region upstream of exon 2 through the 3'-UTR of exon 10. (J:306220)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ets2 Mutation: 41 strains or lines available

References

• Original: J:306220 Kishimoto Y, et al., A novel tissue specific alternative splicing variant mitigates phenotypes in Ets2 frame-shift mutant models. Sci Rep. 2021 Apr 15;11(1):8297
• All: 1 reference(s)