Tg(CLCNKB-cre)#Ttok
Transgene Detail

Summary

• Symbol: Tg(CLCNKB-cre)#Ttok
• Name: transgene insertion, Takeshi Tokudome
• MGI ID: MGI:6718960
• Synonyms: CLK-KB-Cre
• Transgene: Tg(CLCNKB-cre)#Ttok Location: unknown
• Alliance: Tg(CLCNKB-cre)#Ttok page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(CLCNKB-cre)#Ttok expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  CLCNKB (1188)

  Clcnka	(MGI:1329026)
  Clcnkb	(MGI:1930643)

• Mutation details: The transgene consists of an 11-kb 5 flanking region of the human CLC-KB gene fused to Cre recombinase cDNA upstream of the SV40 polyA signal sequence. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:302255)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CLCNKB (human) Summary of all recombinase alleles driven by CLCNKB. Comparative matrix view of recombinase activities Alliance human CLCNKB gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:302255 Otani K, et al., Deficiency of Cardiac Natriuretic Peptide Signaling Promotes Peripartum Cardiomyopathy-Like Remodeling in the Mouse Heart. Circulation. 2020 Feb 18;141(7):571-588
• All: 1 reference(s)