Dock5^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dock5^em1Gpt
• Name: dedicator of cytokinesis 5; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6718927
• Synonyms: Dock5^em1Cflox, Dock5^flox
• Gene: Dock5 Location: Chr14:67989584-68170891 bp, - strand Genetic Position: Chr14, 34.66 cM
• Alliance: Dock5^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 2 to 3 were flanked by loxP sites using CRISPR/Cas9 technology. (J:293217)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dock5 Mutation: 158 strains or lines available

References

• Original: J:306959 Qu H, et al., Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing. Diabetes. 2021 May;70(5):1170-1184
• All: 2 reference(s)