Plaat3^em1Nmz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Plaat3^em1Nmz
• Name: phospholipase A and acyltransferase 3; endonuclease-mediated mutation 1, Noboru Mizushima
• MGI ID: MGI:6718610
• Gene: Plaat3 Location: Chr19:7534824-7565910 bp, + strand Genetic Position: Chr19, 5.33 cM
• Alliance: Plaat3^em1Nmz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 16 bp (ACTGGTGGGGCAGGAG) deletion in exon 4. (J:306889)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plaat3 Mutation: 43 strains or lines available

References

• Original: J:306889 Morishita H, et al., Organelle degradation in the lens by PLAAT phospholipases. Nature. 2021 Apr;592(7855):634-638
• All: 2 reference(s)