Uqcc3^em1Hya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Uqcc3^em1Hya
• Name: ubiquinol-cytochrome c reductase complex assembly factor 3; endonuclease-mediated mutation 1, Hanshuo Yang
• MGI ID: MGI:6718325
• Synonyms: Uqcc3^F
• Gene: Uqcc3 Location: Chr19:8857378-8858287 bp, - strand Genetic Position: Chr19, 5.9 cM
• Alliance: Uqcc3^em1Hya page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• LoxP sites were inserted in exon 1 upstream of the ATG and in exon 2 downstream of the TGA. (J:306534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uqcc3 Mutation: 11 strains or lines available

References

• Original: J:306534 Yang Y, et al., Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma. Cell Rep. 2020 Nov 3;33(5):108340
• All: 2 reference(s)