Runx3^tm1(flpo)Noo
Targeted Allele Detail

Summary

• Symbol: Runx3^tm1(flpo)Noo
• Name: runt related transcription factor 3; targeted mutation 1, C. de Nooij
• MGI ID: MGI:6718261
• Synonyms: Runx3:FlpO
• Gene: Runx3 Location: Chr4:134847963-134905301 bp, + strand Genetic Position: Chr4, 67.19 cM
• Alliance: Runx3^tm1(flpo)Noo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304855
• Parent Cell Line: MM13 (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Runx3^tm1(flpo)Noo expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Runx3 (MGI:102672)

• Mutation details: An IRESFlpOneo cassette was inserted just after the Runx3 stop codon through homologous recombination in mouse embryonic stem cells. (J:304855)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Runx3 (mouse) Summary of all recombinase alleles driven by Runx3. Comparative matrix view of recombinase activities Alliance mouse Runx3 gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx3 Mutation: 24 strains or lines available

References

• Original: J:304855 Oliver KM, et al., Molecular correlates of muscle spindle and Golgi tendon organ afferents. Nat Commun. 2021 Mar 1;12(1):1451
• All: 1 reference(s)