Hexb^em1Mp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hexb^em1Mp
• Name: hexosaminidase B; endonuclease-mediated mutation 1, Marco Prinz
• MGI ID: MGI:6717341
• Synonyms: Hexb^tdTomato
• Gene: Hexb Location: Chr13:97312839-97334865 bp, - strand Genetic Position: Chr13, 50.66 cM
• Alliance: Hexb^em1Mp page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 system was used to knockin the T2A-tdTomato cassette into the Hexb locus by injecting mouse embryos on a C57Bl/6N background. (J:306642)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hexb Mutation: 89 strains or lines available

References

• Original: J:306642 Masuda T, et al., Novel Hexb-based tools for studying microglia in the CNS. Nat Immunol. 2020 Jul;21(7):802-815
• All: 5 reference(s)