Cd19em1.1(icre)Yoba
Endonuclease-mediated Allele Detail
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Symbol: |
Cd19em1.1(icre)Yoba |
Name: |
CD19 antigen; endonuclease-mediated mutation 1.1, Yoshihiro Baba |
MGI ID: |
MGI:6717340 |
Synonyms: |
CD19-iCre |
Gene: |
Cd19 Location: Chr7:126007622-126014061 bp, - strand Genetic Position: Chr7, 69.01 cM, cytoband F3-F4
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Alliance: |
Cd19em1.1(icre)Yoba page
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Germline Transmission: |
Earliest citation of germline transmission:
J:304919
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Parent Cell Line: |
EGR-101 (ES Cell)
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Strain of Origin: |
C57BL/6NSlc
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Allele Type: |
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Endonuclease-mediated (Recombinase) |
Mutation: |
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Insertion
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Cd19em1.1(icre)Yoba expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Cd19 (MGI:88319) |
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Mutation details: The T2A-iCre sequence and neo selection cassette were inserted in-frame to the 3-end of the Cd19 coding sequence immediately upstream of the stop codon using CRISPR/Cas9-mediated homologous recombination technology. Flp-mediated recombination removed the selection cassette.
(J:304919)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Cd19
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cd19 Mutation: |
56 strains or lines available
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Original: |
J:304919 Yasuda T, et al., Generation and characterization of CD19-iCre mice as a tool for efficient and specific conditional gene targeting in B cells. Sci Rep. 2021 Mar 9;11(1):5524 |
All: |
1 reference(s) |
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