Ank1^tm1.1Mnr
Targeted Allele Detail

Summary

• Symbol: Ank1^tm1.1Mnr
• Name: ankyrin 1, erythroid; targeted mutation 1.1, Matthew N Rasband
• MGI ID: MGI:6717196
• Synonyms: Ank1^F
• Gene: Ank1 Location: Chr8:23464860-23640513 bp, + strand Genetic Position: Chr8, 11.42 cM
• Alliance: Ank1^tm1.1Mnr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:310189
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT-IRES-GFP-loxP-NeoStop-FRT-loxP cassette ws introduced to intron 25 and a loxP site was placed in intron 27. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 26 and 27 floxed. (J:310189)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ank1 Mutation: 108 strains or lines available

References

• Original: J:310189 Stevens SR, et al., Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K(+) channels. Elife. 2021 Jun 28;10:e66491
• All: 5 reference(s)