Jazf1^em1Mgn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Jazf1^em1Mgn
• Name: JAZF zinc finger 1; endonuclease-mediated mutation 1, Mark A Magnuson
• MGI ID: MGI:6716237
• Gene: Jazf1 Location: Chr6:52745782-53045616 bp, - strand Genetic Position: Chr6, 25.74 cM
• Alliance: Jazf1^em1Mgn page

Mutation origin

• Strain of Origin: B6J.129(Cg)-Gt(ROSA)26Sor^{tm1.1(CAG-cas9*,-EGFP)Fezh}/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeted of the first coding exon deleted 8 bp and is predicted to produce a truncated protein of 42 amino acids. (J:306470)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Jazf1 Mutation: 22 strains or lines available

References

• Original: J:306470 Osipovich AB, et al., A developmental lineage-based gene co-expression network for mouse pancreatic beta-cells reveals a role for Zfp800 in pancreas development. Development. 2021 Mar 21;148(6):dev196964
• All: 2 reference(s)